Buy 4-Aco DMT | Best 4-Acetoxy DMT (O-Acetylpsilocin)

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4-AcO-DMT-also known as O-acetylpsilocin, 4-acetoxy-DMT, psilacetin, or “synthetic mushrooms”—is a semi-synthetic research chemical in the tryptamine family, which also includes the classic psychedelics like DMT and psilocybin

4-AcO DMT Dose Ranges for Oral Ingestion

  • Microdose: 2.5 – 5 mg
  • Low Dose: 5 – 10 mg
  • Moderate Dose: 10 – 20 mg
  • High Dose: 20 – 40 mg
  • Heroic Dose: 40 mg +

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4-Acetoxy DMT (4-Aco DMT) Analytical Reference Standard, 250mg

4-acetoxy DMT also known as 4-Aco DMT is an O-acetylated psilocin that is believed to be a synthetic prodrug of psilocin, the psychedelic hallucinogen derived from various mushrooms. Although its pharmacological and toxicological properties are not well known, its activity has been proposed to be somewhat similar to that of psilocybin and psilocin. This product is intended for forensic and research applications.


  • Acetylpsilocin
  • 4-acetoxy-N,N-Dimethyltryptamine
  • O-Acetylpsilocin
  • Psilacetin


Formal Name
3-[2-(dimethylamino)ethyl]-1H-indol-4-ol-4-acetate, monohydrochloride
Molecular Formula
C14H18N2O2 • HCl
Formula Weight
A solution in acetonitrile
  • DMF: 30 mg/ml
  • DMSO: 10 mg/ml
  • Ethanol: 20 mg/ml
  • PBS (pH 7.2): 10 mg/ml
219, 277 nm
InChi Code
InChi Key


Wet ice in continental US; may vary elsewhere
≥ 2 years

What is 4-AcO-DMT?

4-AcO-DMT-also known as O-acetylpsilocin, 4-acetoxy-DMT, psilacetin, or “synthetic mushrooms”—is a semi-synthetic research chemical in the tryptamine family, which also includes the classic psychedelics like DMT and psilocybin. 4-AcO seems to be very closely related to the magic mushroom compounds psilocybin and psilocin, and like psilocybin, is speculated to break down into psilocin in the body during first pass metabolism.

In fact, 4-AcO-DMT was first synthesized in the early 1960s by Albert Hofmann, the same chemist who discovered LSD and first synthesized psilocybin. As an employee for the pharmaceutical company Sandoz, Hofmann and his colleague, Franz Troxler, were playing around with molecules similar to psilocin, and patented psilacetin along with four other esters (organic compounds that react to water by producing alcohol) of psilocin in 1963.

But 4-AcO was patented and then largely forgotten, until it reappeared in the 1990s rave scene as a new designer drug. Then in 1999, professor and psychedelic scientist David E. Nichols tried to put it on the map as a safe and cost-effective alternative to psilocybin, because it’s much easier (and cheaper) to synthesize but more than 20 years later, there still haven’t been any clinical studies on the safety, toxicity, or potential efficacy of O-acetylpsilocin, despite its rising popularity among psychonauts.

Today, psilacetin is comes in the form of a brown or off-white powder (technically a fumarate salt) that can be taken orally or intranasally in micro-doses or more, depending how hard you want to trip—which, depending on how many milligrams one takes, can resemble the effects of mushrooms or DMT, causing many to speculate that 4-AcO has psychedelic properties of its own.

4-AcO-DMT Dosage

Before I start to explain what the 4-AcO trip is like, it’s important to emphasize just how dose-dependent the research chemical is. The general consensus among users on message boards and the nine people who filled out a survey I created on 4-AcO, is that lower doses feel like a psilocybin experience, while higher doses start to more so resemble a DMT experience. Or as Sarah*, one of my survey participants, put it, “It was like mushrooms, DMT, and acid in one… like a long DMT trip with the warm and loving feeling of mushrooms, and the mind-blowing experience of acid.”

4-AcO Dose Ranges for Oral Ingestion

  • Microdose: 2.5 – 5 mg
  • Low Dose: 5 – 10 mg
  • Moderate Dose: 10 – 20 mg
  • High Dose: 20 – 40 mg
  • Heroic Dose: 40 mg +

A general reference point indicates that many individuals consider oral doses in the 15 to 20 mg range to closely resemble a 3.5-gram magic mushroom experience. Like all new psychedelics, it’s advisable to commence with a low to moderate dose or even microdose for your initial trip. This approach allows you to familiarize yourself with the terrain before delving into more intense experiences.

For nasal ingestion, doses will differ slightly, as many individuals claim that snorting the powder leads to a stronger but potentially shorter-acting experience. Additionally, a survey participant highlighted the possibility of the powder turning blue in your nostrils. If this occurs, there’s no need for alarm, as it seems to be a common phenomenon.

4-AcO Dose Ranges for Intranasal Ingestion:

  • Microdose: less than 5 mg
  • Low Dose: 5 – 10 mg
  • Moderate Dose: 10 – 20 mg
  • High Dose: 20 – 30 mg
  • Heroic Dose: 30 mg +

For safe dosing, be sure to weigh out your dose on a scale that can read milligrams and if you don’t own one, you should consider investing. They don’t cost more than about $20 and are an easy way to practice harm reduction. Especially with research chemicals that come as powders, a small amount can have a big impact on the strength of the experience.

O-acetylpsilocin Duration

Most folks report an O-acetylpsilocin trip to last more or less the same amount of time as mushrooms but from four to eight hours with an afterglow lasting up to 48 hours after the experience has ended.

Psychonaut Wiki has mapped out the duration as such:

  • Total: 4 – 7 hours
  • Onset: 15 – 40 minutes
  • Come Up: 30 – 75 minutes
  • Peak: 2 to 3.5 hours
  • Offset: 1 – 2 hours
  • After effects: 4 – 48 hours

4-AcO DMT Trip 

The 4-AcO trip is very dose-dependent. The most common way people describe it is the trip being like a crisp, lucid, and warm mushroom experience on low and moderate doses of about 15 to 30 mg. “4-AcO has a very light and joyous character, almost childlike. Like mushrooms but crisper and clearer,” wrote Steven*, one of my survey respondents, who’s tried 4-AcO at doses ranging from 10 to 50 mg several hundred times. “It’s slightly gentler and more simplified of a trip than mushrooms, but almost the same feeling.”

Buy 4-AcO-DMT Deadhead Chemist Microdose | Microdosing Deadhead Chemist 4-AcO-DMT

DMT is illegal in most parts of the world and we do not promote the use of this substance in such areas. For users that decide to use this substance, we provide a complete guide about the substance to ensure that all its users are kept safe.

So What Exactly Is Buy 4-AcO DMT Deadhead Chemist?

N,N-Dimethyltryptamine (DMT) is a psychoactive chemical substance found naturally in some plants, animals, and even the human brain, exposing us to this substance. Some cultures utilize DMT for ritual purposes, aiming to alter their consciousness and mood.

The Amazonians, for instance, utilize DMT found in ayahuasca for their psychedelic experiences. Discovered by Albert Hofmann and Franz Troxler, the same individuals who found LSD, DMT was patented by Sandoz Limited in 1963.

Various methods exist for ingesting DMT, with many opting for its crystal form. Smoking it through a pipe or bong, or injecting it, result in powerful yet short trips, believed to be among the most potent hallucinogenic experiences.

Among the numerous “grey market” research chemicals, Buy 4-AcO DMT Deadhead Chemist stands out as one of the safest. This synthetic psychedelic tryptamine shares structural similarities with the molecules found in “magic mushrooms,” namely psilocybin and psilocin.

Many Benefits Come With The Consumption Of The DMT Microdose 4-ACO-Microdosing/4-Acetoxy-N,N-Dimethyltryptamine (Psilacetin Or 4-AcO DMT)

It creates a feeling of peace and relaxation in the mind and body.
4-Aco enhances the sense of positivity in our mood.
This gives us a stronger feeling of empathy and community.
It gives us the strength to focus and also ensures the mind is free of all negativities.
4-Aco DMT enhances colours and intensifies one’s physical perception.
It energizes and drives us on.
With microdose of DMT users will find an increase in focus, decrease in anxiety, or easier access to flow states

How To Microdose With Buy 4-AcO DMT Deadhead Chemist?

Deadhead Chemist typically sells 4-AcO-DMT in a crystallized or powdered form, facilitating various ingestion methods, including oral consumption. However, the preferred and simplest approach is oral intake, despite the substance’s unfavorable taste.

When determining your desired dose, it is crucial to note that altering a few milligrams can significantly impact your experience. According to scientific analysis and reports, the optimal microdose volume falls between 0.5mg and 5mg. If you’re a novice DMT user, it’s advisable to stick to lower volumes, as doses as high as 5mg can be challenging for some individuals.

For beginners, commencing with 1mg allows you to assess your experience for subsequent measurements. Nevertheless, since most scales are not perfectly accurate with such minute amounts, employing the volumetric microdosing method ensures precise dosage confirmation.

Order 4-aco DMT to put yourself in a psychedelic trip

Buy 4-Aco DMT Quality Drug Online is a synthetically produced psychoactive drug. Its has been suggested by David Nichols to be a potentially useful alternative to psilocybin for pharmacological studies

4-ACO DMT, O-Acetylpsilocin is a synthetically produced psychoactive drug and has been suggested by David Nichols to be a potentially useful alternative to psilocybin for pharmacological studies, as they are both believed to be prodrugs of psilocin.

4-ACO DMT (also known as O-Acetylpsilocin, 4-Acetoxy-DMT, or Psilacetin) is a synthetically produced psychedelic tryptamine. It is the acetylated form of the psilocybin mushroom alkaloid psilocin and is a lower homolog of 4-AcO DMT, 4-AcO-MiPT, nd 4-AcO-DiPT. The compound has been suggested by David Nichols to be a potentially useful alternative to psilocybin for pharmacological studies.

Since they are both believed to be prodrugs of psilocin. Its structural similarities to psilocin and psilocybin results in an identical subjective effect profile and the three compounds can be said to feel indistinguishable from each other. This allows 4-AcO DMT to function as a perfect substitute for psilocybin mushrooms.

4-ACO DMT and several other esters of psilocin were originally patented on January 16, 1963, y Sandoz Ltd. via Albert Hofmann & Franz Troxler. Despite this fact, 4-AcO-DMT remains a psychedelic with a limited history of use. Prior to its release as a grey area compound on the online research chemical market.

4-ACO DMT ‘s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

what makes cheap 4-aco dmt a popular choice amongst DMT drugs

DMT, short for dimethyltryptamine, is considered by many to be among the most powerful psychedelics that we can experience. People who have used DMT report mystical visions that are often far stronger than with other psychedelics.

They feel that they had been taken to alternate realities, interacted with sentient interdimensional beings, and had their worldview changed by visceral experiences that seemed more real than their daily life.

Although the duration of DMT’s effects is short — 10-20 minutes — users claim it feels like days, weeks, and even years of experience unfold within that span. But the most compelling fact about this highly psychoactive substance is that it stands alone among other entheogens as the only one that is naturally found and produced in the human body, a fact that has great implications for its use in the treatment of substance abuse, addiction, and other psychological maladies.

What is 4-Aco-DMT?

In the body, 4-AcO DMT is thought to be deacetylated into psilocin during the t-pass metabolism and passes through the liver. This has not been formally proven and is based on reports that most users cannot tell the difference between these two compounds when ingested to the point that they are often considered as indistinguishable from each other in terms of their subjective effects.

There are, however, claims of subjective differences in effect between the acetylated and non-acetylated forms of psilocin. Some users report that it lasts slightly longer than psilocin while others report that it lasts for a shorter time. Many users report less body load and nausea compared to psilocin. Some users find that the visual distortions produced by 4-AcO DMT more closely resemble those produced by DMT.

EFFECTS of 4-aco DMT

Tactile enhancement – This particular component is perhaps the most overwhelming sensation within the entirety of the 4- experience. It increases the intensity of tactile sensations to such an overwhelming extent that it can induce a sensation of sustained and repeatable full body orgasm within every nerve ending across the entire body to a degree not found within any other psychedelic drug.

The experience of this results in the perception of having difficulty sustaining the act of breathing. It is worth noting, however, that this is not a genuine or dangerous experience of respiratory depression and is considered to be safe.

Bodily control enhancement
Bodily pressures
Changes in gravity
Motor control loss
Perception of increased weight
Pupil dilation
Skin flushing
Temperature regulation suppression
Cognitive effects
Analysis enhancement
Conceptual thinking
Subconscious communication
Emotion enhancement
Increased music appreciation
Memory suppression
Ego death

Additional information


2 grams, 5 grams, 10 grams, 1/2 ounce, 1 ounce

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