4-acetoxy DMT also known as deadhead chemist 4-Aco DMT is an O-acetylated psilocin that is believed to be a synthetic prodrug of psilocin, the psychedelic hallucinogen derived from various mushrooms. Although its pharmacological and toxicological properties are not well known, its activity has been proposed to be somewhat similar to that of psilocybin and psilocin. This product is intended for forensic and research applications.

Deadhead Chemist 4-AcO DMT Dosage

Before I start to explain what tripping with deadhead chemist 4-AcO is like, it’s important to emphasize just how dose-dependent the research chemical is. The general consensus among users on message boards and the nine people who filled out a survey I created on 4-AcO, is that lower doses feel like a psilocybin experience, while higher doses start to more so resemble a DMT experience. Or as Sarah*, one of my survey participants, put it, “It was like mushrooms, DMT, and acid in one… like a long DMT trip with the warm and loving feeling of mushrooms, and the mind-blowing experience of acid.”

Deadhead chemist 4-AcO DMT Dose Ranges for Oral Ingestion: 

• Microdose: 2.5 – 5 mg
• Low Dose: 5 – 10 mg
• Moderate Dose: 10 – 20 mg
• High Dose: 20 – 40 mg
• Heroic Dose: 40 mg +

A general reference point indicates that many individuals consider oral doses in the 15 to 20 mg range to closely resemble a 3.5-gram magic mushroom experience. Like all new psychedelics, it’s advisable to commence with a low to moderate dose or even microdose for your initial trip. This approach allows you to familiarize yourself with the terrain before delving into more intense experiences.

For nasal ingestion, doses will differ slightly, as many individuals claim that snorting the powder leads to a stronger but potentially shorter-acting experience. Additionally, a survey participant highlighted the possibility of the powder turning blue in your nostrils. If this occurs, there’s no need for alarm, as it seems to be a common phenomenon.

Deadhead chemist 4-AcO DMT Dose Ranges for Intranasal Ingestion:

• Microdose: less than 5 mg
• Low Dose: 5 – 10 mg
• Moderate Dose: 10 – 20 mg
• High Dose: 20 – 30 mg
• Heroic Dose: 30 mg +

For safe dosing, be sure to weigh out your dose on a scale that can read milligrams and if you don’t own one, you should consider investing. They don’t cost more than about $20 and are an easy way to practice harm reduction. Especially with research chemicals that come as powders, a small amount can have a big impact on the strength of the experience.

O-acetylpsilocin Duration

Most folks report an O-acetylpsilocin trip to last more or less the same amount of time as mushrooms but from four to eight hours with an afterglow lasting up to 48 hours after the experience has ended.

Psychonaut Wiki has mapped out the duration as such:

• Total: 4 – 7 hours
• Onset: 15 – 40 minutes
• Come Up: 30 – 75 minutes
• Peak: 2 to 3.5 hours
• Offset: 1 – 2 hours
• After effects: 4 – 48 hours

Deadhead Chemist 4-AcO DMT Trip 

The 4-AcO trip is very dose-dependent. The most common way people describe it is the trip being like a crisp, lucid, and warm mushroom experience on low and moderate doses of about 15 to 30 mg. “Deadhead chemist 4-AcO has a very light and joyous character, almost childlike. Like mushrooms but crisper and clearer,” wrote Steven*, one of my survey respondents, who’s tried 4-AcO at doses ranging from 10 to 50 mg several hundred times. “It’s slightly gentler and more simplified of a trip than mushrooms, but almost the same feeling.”